Anti-KCNJ6 antibody (Cytoplasmic Domain) (STJ13101265)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the cytoplasmic domain of human KCNJ6 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
General Information
| Short Description | Rabbit polyclonal anti-KCNJ6 (Cytoplasmic Domain) for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | KCNJ6 |
| Gene ID | 3763 |
| Uniprot ID | KCNJ6_HUMAN |
| Immunogen | A synthetic peptide from the cytoplasmic domain of human KCNJ6 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
| Immunogen Region | Cytoplasmic Domain |
| Specificity | Specific for KCNJ6. |
Additional Info
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. |
| Protein Name | G Protein-Activated Inward Rectifier Potassium Channel 2Girk-2Bir1Inward Rectifier K(+ Channel Kir3.2Katp-2Potassium Channel - Inwardly Rectifying Subfamily J Member 6 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G Protein-Activated Inward Rectifier Potassium Channel 2 antibodyAnti-Girk-2 antibodyAnti-Bir1 antibodyAnti-Inward Rectifier K(+ Channel Kir3.2 antibodyAnti-Katp-2 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 6 antibodyAnti-KCNJ6 antibodyAnti-GIRK2 antibodyAnti-KATP2 antibodyAnti-KCNJ7 antibody |
Information sourced from Uniprot.org