| Tissue Specificity | Heart, skeletal muscle, and several different brain regions including the hippocampus. |
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. |
| Protein Name | Inward Rectifier Potassium Channel 4Hirk2Hrk1Hippocampal Inward RectifierHirInward Rectifier K(+ Channel Kir2.3Irk-3Potassium Channel - Inwardly Rectifying Subfamily J Member 4 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-1296053Reactome: R-HSA-5576886Reactome: R-HSA-997272 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell MembraneCytoplasmic Vesicle MembraneTax1bp3 Binding Promotes Dissociation Of Kcnj4 From Lin7 Famaly Members And Kcnj4 Internalization |
| Alternative Antibody Names | Anti-Inward Rectifier Potassium Channel 4 antibodyAnti-Hirk2 antibodyAnti-Hrk1 antibodyAnti-Hippocampal Inward Rectifier antibodyAnti-Hir antibodyAnti-Inward Rectifier K(+ Channel Kir2.3 antibodyAnti-Irk-3 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 4 antibodyAnti-KCNJ4 antibodyAnti-IRK3 antibody |
Information sourced from Uniprot.org
