| Short Description : | Rabbit polyclonal KCNJ15 (221-375) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KCNJ15 |
| Gene ID: | 3772 |
| Uniprot ID: | KCJ15_HUMAN |
| Immunogen Region: | 221-375 |
| Immunogen Sequence: | VTKEGERILLNQATVKFHVD SSSESPFLILPMTFYHVLDE TSPLRDLTPQNLKEKEFELV VLLNATVESTSAVCQSRTSY IPEEIYWGFEFVPVVSLSKN GKYVADFSQFEQIRKSPDCT FYCADSEKQQLEEKYRQEDQ RERELRTLLLQQSNV |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 221-375 of human KCNJ15 (NP_002234.2). |
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. |
| Protein Name | Atp-Sensitive Inward Rectifier Potassium Channel 15Inward Rectifier K(+ Channel Kir1.3Inward Rectifier K(+ Channel Kir4.2Potassium Channel - Inwardly Rectifying Subfamily J Member 15 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Atp-Sensitive Inward Rectifier Potassium Channel 15 antibodyAnti-Inward Rectifier K(+ Channel Kir1.3 antibodyAnti-Inward Rectifier K(+ Channel Kir4.2 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 15 antibodyAnti-KCNJ15 antibodyAnti-KCNJ14 antibody |
Information sourced from Uniprot.org
