Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-KCNJ15 (221-375) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:200-1:2000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
KCNJ15 |
Gene ID: |
3772 |
Uniprot ID: |
KCJ15_HUMAN |
Immunogen Region: |
221-375 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 221-375 of human KCNJ15 (NP_002234.2). |
Immunogen Sequence: |
VTKEGERILLNQATVKFHVD SSSESPFLILPMTFYHVLDE TSPLRDLTPQNLKEKEFELV VLLNATVESTSAVCQSRTSY IPEEIYWGFEFVPVVSLSKN GKYVADFSQFEQIRKSPDCT FYCADSEKQQLEEKYRQEDQ RERELRTLLLQQSNV |
Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. |
Protein Name | Atp-Sensitive Inward Rectifier Potassium Channel 15Inward Rectifier K(+ Channel Kir1.3Inward Rectifier K(+ Channel Kir4.2Potassium Channel - Inwardly Rectifying Subfamily J Member 15 |
Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Atp-Sensitive Inward Rectifier Potassium Channel 15 antibodyAnti-Inward Rectifier K(+ Channel Kir1.3 antibodyAnti-Inward Rectifier K(+ Channel Kir4.2 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 15 antibodyAnti-KCNJ15 antibodyAnti-KCNJ14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance