| Function | Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel that mediates outward-rectifying potassium currents which, on depolarization, reaches a steady-state level and do not inactivate. The kinetic is characterized by a slow activation time course and a small voltage dependence of the activation time constants, therefore, starts to open at more negative voltages. The activation kinetics depend on the prepulse potential and external divalent cation concentration. The time course of activation is biphasic with a fast and a slowly activating current component. With negative prepulses, the current activation is delayed and slowed down several fold, whereas more positive prepulses speed up activation, therefore the activation rate depends on holding potential. |
| Protein Name | Voltage-Gated Delayed Rectifier Potassium Channel Kcnh5Ether-A-Go-Go Potassium Channel 2Heag2Potassium Voltage-Gated Channel Subfamily H Member 5Voltage-Gated Potassium Channel Subunit Kv10.2 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Gated Delayed Rectifier Potassium Channel Kcnh5 antibodyAnti-Ether-A-Go-Go Potassium Channel 2 antibodyAnti-Heag2 antibodyAnti-Potassium Voltage-Gated Channel Subfamily H Member 5 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv10.2 antibodyAnti-KCNH5 antibodyAnti-EAG2 antibody |
Information sourced from Uniprot.org
