Anti-KCNAB3 antibody (293-342 aa) (STJ93882)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human KCNAB3 at the amino acid range 293-342
General Information
| Short Description | Rabbit polyclonal anti-Voltage-gated potassium channel subunit beta-3 channel subunit beta-3 (293-342 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KCNAB3 |
| Gene ID | 9196 |
| Uniprot ID | KCAB3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human KCNAB3 at the amino acid range 293-342 |
| Immunogen Region | 293-342 aa |
| Specificity | KV Beta.3 Polyclonal Antibody detects endogenous levels of KV Beta.3 protein. |
Additional Info
| Function | Regulatory subunit of the voltage-gated potassium (Kv) channels composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunit. The beta-3/KCNAB3 subunit may mediate closure of potassium channels. Increases inactivation of Kv1.5/KCNA5 alpha subunit-containing channels. May display nicotinamide adenine dinucleotide phosphate (NADPH)-dependent aldoketoreductase activity. The binding of oxidized and reduced NADP(H) cofactors may be required for the regulation of potassium channel activity. |
| Protein Name | Voltage-Gated Potassium Channel Subunit Beta-3K(+ Channel Subunit Beta-3Kv-Beta-3 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Voltage-Gated Potassium Channel Subunit Beta-3 antibodyAnti-K(+ Channel Subunit Beta-3 antibodyAnti-Kv-Beta-3 antibodyAnti-KCNAB3 antibodyAnti-KCNA3B antibody |
Information sourced from Uniprot.org