Tissue Specificity | Expressed in testis, restricted to Sertoli cells (at protein level). |
Function | Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays. Has microtubule-severing activity in vitro. |
Protein Name | Katanin P60 Atpase-Containing Subunit A-Like 1Katanin P60 Subunit A-Like 1P60 Katanin-Like 1 |
Cellular Localisation | CytoplasmCytoskeletonSpindle PoleSpindleColocalizes With Microtubules Throughout The Basal And Adluminal Compartments Of Sertoli CellsLocalizes Within The CytoplasmPartially Overlapping With MicrotubulesIn Interphase And To The Mitotic Spindle And Spindle Poles During Mitosis |
Alternative Antibody Names | Anti-Katanin P60 Atpase-Containing Subunit A-Like 1 antibodyAnti-Katanin P60 Subunit A-Like 1 antibodyAnti-P60 Katanin-Like 1 antibodyAnti-KATNAL1 antibody |
Information sourced from Uniprot.org