| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KANSL3 |
| Gene ID: | 55683 |
| Uniprot ID: | KANL3_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human KANSL3 (NP_001108488.1). |
| Immunogen Sequence: | MAHRGGERDFQTSARRMGTS LLFQLSVHERELDLVFLDHS YAKPWSAHPDASSARPTRML FVTPRRQHESTIESDVPIDV ETVTSTPMPLYDNQKARSVM NECERHVIFARTDADAPPPP EDWEEHVNRTGWTMAQNKLF NKILKALQSDRLARLANEGA CNEPVLRRVAVDKCARRVRQ ALASVSWDTKLIQWLHTTLV |
| Function | Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation. The NSL complex also acts as a regulator of gene expression in mitochondria. Within the NSL complex, KANSL3 is required to promote KAT8 association with mitochondrial DNA. |
| Protein Name | Kat8 Regulatory Nsl Complex Subunit 3Nsl Complex Protein Nsl3Non-Specific Lethal 3 HomologSerum Inhibited-Related ProteinTestis Development Protein Prtd |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
| Cellular Localisation | NucleusMitochondrion |
| Alternative Antibody Names | Anti-Kat8 Regulatory Nsl Complex Subunit 3 antibodyAnti-Nsl Complex Protein Nsl3 antibodyAnti-Non-Specific Lethal 3 Homolog antibodyAnti-Serum Inhibited-Related Protein antibodyAnti-Testis Development Protein Prtd antibodyAnti-KANSL3 antibodyAnti-KIAA1310 antibodyAnti-NSL3 antibodyAnti-PRTD antibodyAnti-SI1 antibody |
Information sourced from Uniprot.org