| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ANOS1 |
| Gene ID: | 3730 |
| Uniprot ID: | KALM_HUMAN |
| Immunogen Region: | 200-300 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human KAL1 (NP_000207.2). |
| Immunogen Sequence: | LEVKWSSKFNISIEPVIYVV QRRWNYGIHPSEDDATHWQT VAQTTDERVQLTDIRPSRWY QFRVAAVNVHGTRGFTAPSK HFRSSKDPSAPPAPANLRLA N |
| Tissue Specificity | Expressed in the cerebellum (at protein level). |
| Post Translational Modifications | N-glycosylated. May be proteolytically cleaved at the cell surface and released from the cell surface. |
| Function | Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex. Chemoattractant for fetal olfactory epithelial cells. |
| Protein Name | Anosmin-1Adhesion Molecule-Like X-LinkedKallmann Syndrome Protein |
| Database Links | Reactome: R-HSA-190373Reactome: R-HSA-5654726 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSecretedProteolytic Cleavage May Release It From The Cell Surface Into The Extracellular Space |
| Alternative Antibody Names | Anti-Anosmin-1 antibodyAnti-Adhesion Molecule-Like X-Linked antibodyAnti-Kallmann Syndrome Protein antibodyAnti-ANOS1 antibodyAnti-ADMLX antibodyAnti-KAL antibodyAnti-KAL1 antibodyAnti-KALIG1 antibody |
Information sourced from Uniprot.org