| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-JAKMIP1 (337-626) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
JAKMIP1 |
| Gene ID: |
152789 |
| Uniprot ID: |
JKIP1_HUMAN |
| Immunogen Region: |
337-626 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 337-626 of human JAKMIP1 (NP_653321.1). |
| Immunogen Sequence: |
KRMNKKNEDLLQSIQRMEEK IKNLTRENVEMKEKLSAQAS LKRHTSLNDLSLTRDEQEIE FLRLQVLEQQHVIDDLSLER ERLLRSKRHRGKSLKPPKKH VVETFFGFDEESVDSETLSE TSYNTDRTDRTPATPEEDLD DATAREEADLRFCQLTREYQ ALQRAYALLQEQVGGTLDAE REARTREQLQADLLRCQAKI EDLEKLLVEKGQDSKWVEEK QLLIRTNQDLLEKIYRLEM |
| Tissue Specificity | Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine. |
| Function | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. |
| Protein Name | Janus Kinase And Microtubule-Interacting Protein 1Gaba-B Receptor-Binding ProteinMultiple Alpha-Helices And Rna-Linker Protein 1Marlin-1 |
| Cellular Localisation | CytoplasmCytoskeletonMembranePeripheral Membrane ProteinColocalizes With The Microtubule NetworkLocalizes To The Cell Body And Neurites Of Hippocampal Neurons Where It Accumulates In GranulesLocalizes To The Tail And To A Lower Extent To The Head Of Sperm Cells |
| Alternative Antibody Names | Anti-Janus Kinase And Microtubule-Interacting Protein 1 antibodyAnti-Gaba-B Receptor-Binding Protein antibodyAnti-Multiple Alpha-Helices And Rna-Linker Protein 1 antibodyAnti-Marlin-1 antibodyAnti-JAKMIP1 antibodyAnti-GABABRBP antibodyAnti-JAMIP1 antibodyAnti-MARLIN1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
