Anti-JAKMIP1 antibody (337-626) (STJ115719)

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STJ115719
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: JAKMIP1
Gene ID: 152789
Uniprot ID: JKIP1_HUMAN
Immunogen Region: 337-626
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 337-626 of human JAKMIP1 (NP_653321.1).
Immunogen Sequence: KRMNKKNEDLLQSIQRMEEK IKNLTRENVEMKEKLSAQAS LKRHTSLNDLSLTRDEQEIE FLRLQVLEQQHVIDDLSLER ERLLRSKRHRGKSLKPPKKH VVETFFGFDEESVDSETLSE TSYNTDRTDRTPATPEEDLD DATAREEADLRFCQLTREYQ ALQRAYALLQEQVGGTLDAE REARTREQLQADLLRCQAKI EDLEKLLVEKGQDSKWVEEK QLLIRTNQDLLEKIYRLEM
Tissue Specificity Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.
Function Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
Protein Name Janus Kinase And Microtubule-Interacting Protein 1
Gaba-B Receptor-Binding Protein
Multiple Alpha-Helices And Rna-Linker Protein 1
Marlin-1
Cellular Localisation Cytoplasm
Cytoskeleton
Membrane
Peripheral Membrane Protein
Colocalizes With The Microtubule Network
Localizes To The Cell Body And Neurites Of Hippocampal Neurons Where It Accumulates In Granules
Localizes To The Tail And To A Lower Extent To The Head Of Sperm Cells
Alternative Antibody Names Anti-Janus Kinase And Microtubule-Interacting Protein 1 antibody
Anti-Gaba-B Receptor-Binding Protein antibody
Anti-Multiple Alpha-Helices And Rna-Linker Protein 1 antibody
Anti-Marlin-1 antibody
Anti-JAKMIP1 antibody
Anti-GABABRBP antibody
Anti-JAMIP1 antibody
Anti-MARLIN1 antibody

Information sourced from Uniprot.org