Tissue Specificity | Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine. |
Function | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. |
Protein Name | Janus Kinase And Microtubule-Interacting Protein 1Gaba-B Receptor-Binding ProteinMultiple Alpha-Helices And Rna-Linker Protein 1Marlin-1 |
Cellular Localisation | CytoplasmCytoskeletonMembranePeripheral Membrane ProteinColocalizes With The Microtubule NetworkLocalizes To The Cell Body And Neurites Of Hippocampal Neurons Where It Accumulates In GranulesLocalizes To The Tail And To A Lower Extent To The Head Of Sperm Cells |
Alternative Antibody Names | Anti-Janus Kinase And Microtubule-Interacting Protein 1 antibodyAnti-Gaba-B Receptor-Binding Protein antibodyAnti-Multiple Alpha-Helices And Rna-Linker Protein 1 antibodyAnti-Marlin-1 antibodyAnti-JAKMIP1 antibodyAnti-GABABRBP antibodyAnti-JAMIP1 antibodyAnti-MARLIN1 antibody |
Information sourced from Uniprot.org