| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITPKA |
| Gene ID: | 3706 |
| Uniprot ID: | IP3KA_HUMAN |
| Immunogen Region: | 141-461 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 141-461 of human ITPKA (NP_002211.1). |
| Immunogen Sequence: | LLSDSESRSRGNVQLEAGED VGQKNHWQKIRTMVNLPVIS PFKKRYAWVQLAGHTGSFKA AGTSGLILKRCSEPERYCLA RLMADALRGCVPAFHGVVER DGESYLQLQDLLDGFDGPCV LDCKMGVRTYLEEELTKARE RPKLRKDMYKKMLAVDPEAP TEEEHAQRAVTKPRYMQWRE GISSSTTLGFRIEGIKKADG SCSTDFKTTRSREQVLRVFE EFVQGDEEVLRRYLNRLQQ |
| Tissue Specificity | Expressed in brain. |
| Function | Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. |
| Protein Name | Inositol-Trisphosphate 3-Kinase AInositol 1 -4 -5-Trisphosphate 3-Kinase AIp3 3-Kinase AIp3k AInsp 3-Kinase A |
| Database Links | Reactome: R-HSA-1855204 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Inositol-Trisphosphate 3-Kinase A antibodyAnti-Inositol 1 -4 -5-Trisphosphate 3-Kinase A antibodyAnti-Ip3 3-Kinase A antibodyAnti-Ip3k A antibodyAnti-Insp 3-Kinase A antibodyAnti-ITPKA antibody |
Information sourced from Uniprot.org