| Short Description : | Rabbit polyclonal ITIH3 (35-180) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITIH3 |
| Gene ID: | 3699 |
| Uniprot ID: | ITIH3_HUMAN |
| Immunogen Region: | 35-180 |
| Immunogen Sequence: | LPEGVANGIEVYSTKINSKV TSRFAHNVVTMRAVNRADTA KEVSFDVELPKTAFITNFTL TIDGVTYPGNVKEKEVAKKQ YEKAVSQGKTAGLVKASGRK LEKFTVSVNVAAGSKVTFEL TYEELLKRHKGKYEMYLKVQ PKQLVK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-180 of human ITIH3 (NP_002208.3). |
| Post Translational Modifications | Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage. |
| Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. |
| Protein Name | Inter-Alpha-Trypsin Inhibitor Heavy Chain H3Iti Heavy Chain H3Iti-Hc3Inter-Alpha-Inhibitor Heavy Chain 3Serum-Derived Hyaluronan-Associated ProteinShap |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Inter-Alpha-Trypsin Inhibitor Heavy Chain H3 antibodyAnti-Iti Heavy Chain H3 antibodyAnti-Iti-Hc3 antibodyAnti-Inter-Alpha-Inhibitor Heavy Chain 3 antibodyAnti-Serum-Derived Hyaluronan-Associated Protein antibodyAnti-Shap antibodyAnti-ITIH3 antibody |
Information sourced from Uniprot.org
