| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITIH3 |
| Gene ID: | 3699 |
| Uniprot ID: | ITIH3_HUMAN |
| Immunogen Region: | 35-180 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-180 of human ITIH3 (NP_002208.3). |
| Immunogen Sequence: | LPEGVANGIEVYSTKINSKV TSRFAHNVVTMRAVNRADTA KEVSFDVELPKTAFITNFTL TIDGVTYPGNVKEKEVAKKQ YEKAVSQGKTAGLVKASGRK LEKFTVSVNVAAGSKVTFEL TYEELLKRHKGKYEMYLKVQ PKQLVK |
| Post Translational Modifications | Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage. |
| Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. |
| Protein Name | Inter-Alpha-Trypsin Inhibitor Heavy Chain H3Iti Heavy Chain H3Iti-Hc3Inter-Alpha-Inhibitor Heavy Chain 3Serum-Derived Hyaluronan-Associated ProteinShap |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Inter-Alpha-Trypsin Inhibitor Heavy Chain H3 antibodyAnti-Iti Heavy Chain H3 antibodyAnti-Iti-Hc3 antibodyAnti-Inter-Alpha-Inhibitor Heavy Chain 3 antibodyAnti-Serum-Derived Hyaluronan-Associated Protein antibodyAnti-Shap antibodyAnti-ITIH3 antibody |
Information sourced from Uniprot.org