| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITGB5 |
| Gene ID: | 3693 |
| Uniprot ID: | ITB5_HUMAN |
| Immunogen Region: | 490-720 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 490-720 of human ITGB5 (NP_002204.2). |
| Immunogen Sequence: | SPGYLGTRCECQDGENQSVY QNLCREAEGKPLCSGRGDCS CNQCSCFESEFGKIYGPFCE CDNFSCARNKGVLCSGHGEC HCGECKCHAGYIGDNCNCST DISTCRGRDGQICSERGHCL CGQCQCTEPGAFGEMCEKCP TCPDACSTKRDCVECLLLHS GKPDNQTCHSLCRDEVITWV DTIVKDDQEAVLCFYKTAKD CVMMFTYVELPSGKSNLTVL REPECGNTPNA |
| Function | Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. (Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C. |
| Protein Name | Integrin Beta-5 |
| Database Links | Reactome: R-HSA-1236973 Reactome: R-HSA-2129379 Reactome: R-HSA-216083 Reactome: R-HSA-2173789 Reactome: R-HSA-3000170 Reactome: R-HSA-3000178 Reactome: R-HSA-445355 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Beta-5 antibody Anti-ITGB5 antibody |
Information sourced from Uniprot.org