| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ITGAE (19-200) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ITGAE |
| Gene ID: |
3682 |
| Uniprot ID: |
ITAE_HUMAN |
| Immunogen Region: |
19-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 19-200 of human ITGAE (NP_002199.3). |
| Immunogen Sequence: |
FNVDVARPWLTPKGGAPFVL SSLLHQDPSTNQTWLLVTSP RTKRTPGPLHRCSLVQDEIL CHPVEHVPIPKGRHRGVTVV RSHHGVLICIQVLVRRPHSL SSELTGTCSLLGPDLRPQAQ ANFFDLENLLDPDARVDTGD CYSNKEGGGEDDVNTARQRR ALEKEEEEDKEEEEDEEEEE AG |
| Tissue Specificity | Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
| Function | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
| Protein Name | Integrin Alpha-EHml-1 AntigenIntegrin Alpha-IelMucosal Lymphocyte 1 AntigenCd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain |
| Database Links | Reactome: R-HSA-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-E antibodyAnti-Hml-1 Antigen antibodyAnti-Integrin Alpha-Iel antibodyAnti-Mucosal Lymphocyte 1 Antigen antibodyAnti-Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain antibodyAnti-ITGAE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
