| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IRF2BP1 |
| Gene ID: | 26145 |
| Uniprot ID: | I2BP1_HUMAN |
| Immunogen Region: | 60-240 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-240 of human IRF2BP1 (NP_056464.1). |
| Immunogen Sequence: | VLPEGRSPGPPALKHPATKD LAAAAAQGPQLPPPQAQPQP SGTGGGVSGQDRYDRATSSG RLPLPSPALEYTLGSRLANG LGREEAVAEGARRALLGSMP GLMPPGLLAAAVSGLGSRGL TLAPGLSPARPLFGSDFEKE KQQRNADCLAELNEAMRGRA EEWHGRPKAVREQLLALSAC A |
| Function | Acts as a transcriptional corepressor in a IRF2-dependent manner.this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. |
| Protein Name | Interferon Regulatory Factor 2-Binding Protein 1Irf-2-Binding Protein 1Irf-2bp1Probable E3 Ubiquitin-Protein Ligase Irf2bp1Probable Ring-Type E3 Ubiquitin Transferase Irf2bp1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Interferon Regulatory Factor 2-Binding Protein 1 antibodyAnti-Irf-2-Binding Protein 1 antibodyAnti-Irf-2bp1 antibodyAnti-Probable E3 Ubiquitin-Protein Ligase Irf2bp1 antibodyAnti-Probable Ring-Type E3 Ubiquitin Transferase Irf2bp1 antibodyAnti-IRF2BP1 antibody |
Information sourced from Uniprot.org