• Western blot analysis of extracts of various cell lines, using IRF2BP1 antibody (STJ117811) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-IRF2BP1 antibody (60-240) (STJ117811)

SKU:
STJ117811

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-IRF2BP1 (60-240) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IRF2BP1
Gene ID: 26145
Uniprot ID: I2BP1_HUMAN
Immunogen Region: 60-240
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-240 of human IRF2BP1 (NP_056464.1).
Immunogen Sequence: VLPEGRSPGPPALKHPATKD LAAAAAQGPQLPPPQAQPQP SGTGGGVSGQDRYDRATSSG RLPLPSPALEYTLGSRLANG LGREEAVAEGARRALLGSMP GLMPPGLLAAAVSGLGSRGL TLAPGLSPARPLFGSDFEKE KQQRNADCLAELNEAMRGRA EEWHGRPKAVREQLLALSAC A
Function Acts as a transcriptional corepressor in a IRF2-dependent manner.this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.
Protein Name Interferon Regulatory Factor 2-Binding Protein 1
Irf-2-Binding Protein 1
Irf-2bp1
Probable E3 Ubiquitin-Protein Ligase Irf2bp1
Probable Ring-Type E3 Ubiquitin Transferase Irf2bp1
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Interferon Regulatory Factor 2-Binding Protein 1 antibody
Anti-Irf-2-Binding Protein 1 antibody
Anti-Irf-2bp1 antibody
Anti-Probable E3 Ubiquitin-Protein Ligase Irf2bp1 antibody
Anti-Probable Ring-Type E3 Ubiquitin Transferase Irf2bp1 antibody
Anti-IRF2BP1 antibody

Information sourced from Uniprot.org

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