| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Inositol 1, 4, 5-triphosphate receptor associated 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IRAG2 |
| Gene ID: |
4033 |
| Uniprot ID: |
IRAG2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of LRMP at Human |
| Immunogen: |
Synthesized peptide derived from human LRMP |
| Post Translational Modifications | The removal of the C-terminal lumenal domain occurs by proteolytic processing. |
| Function | Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules.this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion. Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules. |
| Protein Name | Inositol 1 -4 -5-Triphosphate Receptor Associated 2Lymphoid-Restricted Membrane ProteinProtein Jaw1 Cleaved Into - Processed Inositol 1 -4 -5-Triphosphate Receptor Associated 2 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Processed Inositol 145-Triphosphate Receptor Associated 2: CytoplasmEndoplasmic Reticulum MembraneSingle-Pass Type Iv Membrane ProteinNucleus EnvelopeCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindle PoleChromosomeColocalized With Itpr3 On The Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Inositol 1 -4 -5-Triphosphate Receptor Associated 2 antibodyAnti-Lymphoid-Restricted Membrane Protein antibodyAnti-Protein Jaw1 Cleaved Into - Processed Inositol 1 -4 -5-Triphosphate Receptor Associated 2 antibodyAnti-IRAG2 antibodyAnti-JAW1 antibodyAnti-LRMP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
