| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Inositol-pentakisphosphate 2-kinaseP5 2-kinase (11-60 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IPPK |
| Gene ID: | 64768 |
| Uniprot ID: | IPPK_HUMAN |
| Immunogen Region: | 11-60 aa |
| Specificity: | InsP5 2-kinase Polyclonal Antibody detects endogenous levels of InsP5 2-kinase protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human IPPK at the amino acid range 11-60 |
| Function | Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis. |
| Protein Name | Inositol-Pentakisphosphate 2-KinaseIpk1 HomologInositol-1 -3 -4 -5 -6-Pentakisphosphate 2-KinaseIns(1 -3 -4 -5 -6p5 2-KinaseInsp5 2-Kinase |
| Database Links | Reactome: R-HSA-1855167Reactome: R-HSA-1855191 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Inositol-Pentakisphosphate 2-Kinase antibodyAnti-Ipk1 Homolog antibodyAnti-Inositol-1 -3 -4 -5 -6-Pentakisphosphate 2-Kinase antibodyAnti-Ins(1 -3 -4 -5 -6p5 2-Kinase antibodyAnti-Insp5 2-Kinase antibodyAnti-IPPK antibodyAnti-C9orf12 antibody |
Information sourced from Uniprot.org