Anti-Ionized calcium-binding adapter molecule 1 antibody (C-Term) (STJA0040990)

SKU:
STJA0040990-50
£528.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: ICC/IHC-F/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal anti-Ionized calcium-binding adapter molecule 1 (C-Term) for use in ICC, IHC-F and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilized with sodium azide.
Purification: Whole serum
Dilution Range: WB 1:1000-1:5000
IHC 1:2000-1:5000
ICC 1:1000-1:5000
Storage Instruction: Spin vial briefly before opening. Reconstitute with 50 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at-20°C for long-term s
Gene Symbol: AIF1
Gene ID: 199
Uniprot ID: AIF1_HUMAN
Immunogen Region: C-Term
Specificity: Human, reacts with human, rat, mouse.
Immunogen: C-terminal peptide of human IBA1 protein coupled to KLH.
Immunogen Sequence: Human
Tissue Specificity Detected in T-lymphocytes and peripheral blood mononuclear cells.
Post Translational Modifications Phosphorylated on serine residues.
Function Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Protein Name Allograft Inflammatory Factor 1
Aif-1
Ionized Calcium-Binding Adapter Molecule 1
Protein G1
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Ruffle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Phagocytic Cup
Associated With The Actin Cytoskeleton At Membrane Ruffles And At Sites Of Phagocytosis
Alternative Antibody Names Anti-Allograft Inflammatory Factor 1 antibody
Anti-Aif-1 antibody
Anti-Ionized Calcium-Binding Adapter Molecule 1 antibody
Anti-Protein G1 antibody
Anti-AIF1 antibody
Anti-G1 antibody
Anti-IBA1 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0040713 Anti-Ionized calcium binding adapter molecule 1 antibody (C-Term) (STJA0040713) Chicken Polyclonal Human/Mouse/Rat ICC/IHC-F/WB
STJ70630 Anti-MBL2/Mannan-Binding Lectin antibody (C-Term) (STJ70630) Goat Polyclonal Human Pep-ELISA/WB
STJA0040987 Anti-Methyl-CpG-binding protein 2 antibody (C-Term) (STJA0040987) Rabbit Polyclonal Human/Mouse/Rat IHC-F/WB
STJ71199 Anti-Neurexin 1 antibody (C-Term) (STJ71199) Goat Polyclonal Human/Mouse/Rat/Dog Pep-ELISA/WB/FC
STJ71933 Anti-Copine 1 antibody (C-Term) (STJ71933) Goat Polyclonal Human Pep-ELISA/WB

Related Products

!