| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-INTS8 (600-800) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
INTS8 |
| Gene ID: |
55656 |
| Uniprot ID: |
INT8_HUMAN |
| Immunogen Region: |
600-800 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 600-800 of human INTS8 (NP_060334.2). |
| Immunogen Sequence: |
VTEFSPKLRQVMLNEMLLLD IHTHEAGTGQAGERPPSDLI SRVRGYLEMRLPDIPLRQVI AEECVAFMLNWRENEYLTLQ VPAFLLQSNPYVKLGQLLAA TCKELPGPKESRRTAKDLWE VVVQICSVSSQHKRGNDGRV SLIKQRESTLGIMYRSELLS FIKKLREPLVLTIILSLFVK LHNVREDIVNDITAEHISIW P |
| Function | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
| Protein Name | Integrator Complex Subunit 8Int8Protein Kaonashi-1 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Integrator Complex Subunit 8 antibodyAnti-Int8 antibodyAnti-Protein Kaonashi-1 antibodyAnti-INTS8 antibodyAnti-C8orf52 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
