| Tissue Specificity | Widely expressed. Tends to be up-regulated in seminomas compared to normal testis. |
| Function | Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. |
| Protein Name | Integrator Complex Subunit 13Cell Cycle Regulator Mat89bb HomologGerm Cell Tumor 1Protein Asunder HomologSarcoma Antigen Ny-Sar-95 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | NucleusCytoplasmNuclear Location Is Required For Recruitment Of Dynein Motors To Nuclear Envelope At G2/M |
| Alternative Antibody Names | Anti-Integrator Complex Subunit 13 antibodyAnti-Cell Cycle Regulator Mat89bb Homolog antibodyAnti-Germ Cell Tumor 1 antibodyAnti-Protein Asunder Homolog antibodyAnti-Sarcoma Antigen Ny-Sar-95 antibodyAnti-INTS13 antibodyAnti-ASUN antibodyAnti-C12orf11 antibodyAnti-GCT1 antibody |
Information sourced from Uniprot.org
