| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4957RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:10000-1:80000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
INTS13 |
| Gene ID: |
55726 |
| Uniprot ID: |
INT13_HUMAN |
| Immunogen Region: |
200-300 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human ASUN/INTS13. (NP_060634.2). |
| Immunogen Sequence: |
QKCELVLIHTYPVGEDSLVS DRSKKELSPVLTSEVHSVRA GRHLATKLNILVQQHFDLAS TTITNIPMKEEQHANTSANY DVELLHHKDAHVDFLKSGDS H |
| Tissue Specificity | Widely expressed. Tends to be up-regulated in seminomas compared to normal testis. |
| Function | Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. |
| Protein Name | Integrator Complex Subunit 13Cell Cycle Regulator Mat89bb HomologGerm Cell Tumor 1Protein Asunder HomologSarcoma Antigen Ny-Sar-95 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | NucleusCytoplasmNuclear Location Is Required For Recruitment Of Dynein Motors To Nuclear Envelope At G2/M |
| Alternative Antibody Names | Anti-Integrator Complex Subunit 13 antibodyAnti-Cell Cycle Regulator Mat89bb Homolog antibodyAnti-Germ Cell Tumor 1 antibodyAnti-Protein Asunder Homolog antibodyAnti-Sarcoma Antigen Ny-Sar-95 antibodyAnti-INTS13 antibodyAnti-ASUN antibodyAnti-C12orf11 antibodyAnti-GCT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
