| Tissue Specificity | Isoform 1 is expressed in various tissues with stronger expression in liver, kidney and small intestine. Isoform 2 is abundantly expressed in small intestine and to a lower extent in lung and pancreas. |
| Function | May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis. May regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium. |
| Protein Name | Protein Inscuteable Homolog |
| Cellular Localisation | CytoplasmCell CortexUniformly Distributed In The Cytoplasm During InterphaseDuring MetaphaseDetected In The Cell CortexAdjacent To The Mitotic Spindle Poles |
| Alternative Antibody Names | Anti-Protein Inscuteable Homolog antibodyAnti-INSC antibody |
Information sourced from Uniprot.org
