| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phosphatidylinositol polyphosphate 5-phosphatase type IV (490-570 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
INPP5E |
| Gene ID: |
56623 |
| Uniprot ID: |
INP5E_HUMAN |
| Immunogen Region: |
490-570 aa |
| Specificity: |
INP5E Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 490-570 |
| Function | Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Specific for lipid substrates, inactive towards water soluble inositol phosphates. Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability. |
| Protein Name | Phosphatidylinositol Polyphosphate 5-Phosphatase Type Iv72 Kda Inositol Polyphosphate 5-PhosphataseInositol Polyphosphate-5-Phosphatase EPhosphatidylinositol 4 -5-Bisphosphate 5-PhosphatasePhosphatidylinositol-3 -4 -5-Trisphosphate 5-Phosphatase |
| Database Links | Reactome: R-HSA-1660514Reactome: R-HSA-5624958 |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeGolgi ApparatusGolgi Stack MembranePeripheral Membrane ProteinCytoplasmic SideCell MembraneCell ProjectionRuffleNucleusPeripheral Membrane Protein Associated With Golgi Stacks |
| Alternative Antibody Names | Anti-Phosphatidylinositol Polyphosphate 5-Phosphatase Type Iv antibodyAnti-72 Kda Inositol Polyphosphate 5-Phosphatase antibodyAnti-Inositol Polyphosphate-5-Phosphatase E antibodyAnti-Phosphatidylinositol 4 -5-Bisphosphate 5-Phosphatase antibodyAnti-Phosphatidylinositol-3 -4 -5-Trisphosphate 5-Phosphatase antibodyAnti-INPP5E antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
