• Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-Ovarian-cancer, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-Ovarian-cancer, antibody was diluted at 1:100
  • Western blot analysis of PC12 cells using IL-1RII Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-IL1R2 antibody (141-190 aa) (STJ96835)

SKU:
STJ96835

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Interleukin-1 receptor type 2 (141-190 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL1R2
Gene ID: 7850
Uniprot ID: IL1R2_HUMAN
Immunogen Region: 141-190 aa
Specificity: IL-1RII Polyclonal Antibody detects endogenous levels of IL-1RII protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IL1R2 at the amino acid range 141-190
Function Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity.this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Protein Name Interleukin-1 Receptor Type 2
Il-1r-2
Il-1rt-2
Il-1rt2
Cd121 Antigen-Like Family Member B
Cdw121b
Il-1 Type Ii Receptor
Interleukin-1 Receptor Beta
Il-1r-Beta
Interleukin-1 Receptor Type Ii
Cd Antigen Cd121b Cleaved Into - Interleukin-1 Receptor Type 2 - Membrane Form
Mil-1r2
Mil-1rii - Interleukin-1 Receptor Type 2 - Soluble Form
Sil-1r2
Sil-1rii
Database Links Reactome: R-HSA-6783783
Reactome: R-HSA-9020702
Cellular Localisation Isoform Short: Secreted
Isoform Long: Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-1 Receptor Type 2 antibody
Anti-Il-1r-2 antibody
Anti-Il-1rt-2 antibody
Anti-Il-1rt2 antibody
Anti-Cd121 Antigen-Like Family Member B antibody
Anti-Cdw121b antibody
Anti-Il-1 Type Ii Receptor antibody
Anti-Interleukin-1 Receptor Beta antibody
Anti-Il-1r-Beta antibody
Anti-Interleukin-1 Receptor Type Ii antibody
Anti-Cd Antigen Cd121b Cleaved Into - Interleukin-1 Receptor Type 2 - Membrane Form antibody
Anti-Mil-1r2 antibody
Anti-Mil-1rii - Interleukin-1 Receptor Type 2 - Soluble Form antibody
Anti-Sil-1r2 antibody
Anti-Sil-1rii antibody
Anti-IL1R2 antibody
Anti-IL1RB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance