• Western blot analysis of the lysates from HT-29 cells using IGFBP-3 antibody.
  • Western blot analysis of lysates from RAW246.7 cells, using IGFBP-3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis ofmouse braincells using IGFBP3 Polyclonal Antibody diluted at 1：500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).
  • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using IGFBP-3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using IGFBP3 Polyclonal Antibody diluted at 1：500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-IGFBP3 antibody (151-200 aa) (STJ93651)

SKU:
STJ93651

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Insulin-like growth factor-binding protein 3 (151-200 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:100-500
IF ICC 1:100-500
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IGFBP3
Gene ID: 3486
Uniprot ID: IBP3_HUMAN
Immunogen Region: 151-200 aa
Specificity: IGFBP3 Polyclonal Antibody detects endogenous levels of IGFBP3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human IGFBP-3 at the amino acid range 151-200
Post Translational Modifications Phosphorylated by FAM20C in the extracellular medium.
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity. Promotes testicular germ cell apoptosis.
Protein Name Insulin-Like Growth Factor-Binding Protein 3
Ibp-3
Igf-Binding Protein 3
Igfbp-3
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-6803211
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Antibody Names Anti-Insulin-Like Growth Factor-Binding Protein 3 antibody
Anti-Ibp-3 antibody
Anti-Igf-Binding Protein 3 antibody
Anti-Igfbp-3 antibody
Anti-IGFBP3 antibody
Anti-IBP3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance