| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-IFT81 (550-676) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IFT81 |
| Gene ID: |
28981 |
| Uniprot ID: |
IFT81_HUMAN |
| Immunogen Region: |
550-676 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 550-676 of human IFT81 (NP_054774.2). |
| Immunogen Sequence: |
VRRLREECLQEESRYHYTNC MIKNLEVQLRRATDEMKAYI SSDQQEKRKAIREQYTKNTA EQENLGKKLREKQKVIRESH GPNMKQAKMWRDLEQLMECK KQCFLKQQSQTSIGQVIQEG GEDRLIL |
| Tissue Specificity | Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis. |
| Function | Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. Required for proper regulation of SHH signaling. Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella. |
| Protein Name | Intraflagellar Transport Protein 81 HomologCarnitine Deficiency-Associated Protein Expressed In Ventricle 1Cdv-1 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | Cell ProjectionCiliumCytoplasm |
| Alternative Antibody Names | Anti-Intraflagellar Transport Protein 81 Homolog antibodyAnti-Carnitine Deficiency-Associated Protein Expressed In Ventricle 1 antibodyAnti-Cdv-1 antibodyAnti-IFT81 antibodyAnti-CDV1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
