Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Intraflagellar transport protein 74 homolog is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
IFT74 |
Gene ID: |
80173 |
Uniprot ID: |
IFT74_HUMAN |
Specificity: |
This antibody detects endogenous levels of IFT74 at Human, Mouse |
Immunogen: |
Synthesized peptide derived from human IFT74 |
Function | Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis. Essential for flagellogenesis during spermatogenesis. |
Protein Name | Intraflagellar Transport Protein 74 HomologCapillary Morphogenesis Gene 1 ProteinCmg-1Coiled-Coil Domain-Containing Protein 2 |
Database Links | Reactome: R-HSA-5620924 |
Cellular Localisation | Cell ProjectionCiliumCytoplasmic VesicleFlagellumSecretory VesicleAcrosomeLocalizes Along Primary Cilia At Interphase And Around The Basal Body/Centriole At Interphase And MitosisIn Male Germ CellsStrongly Expressed In The Vesicles Of Spermatocytes And Round Spermatids And Also In The Acrosome And Centrosome Regions Of Elongating Spermatids And In Developing Sperm Tails |
Alternative Antibody Names | Anti-Intraflagellar Transport Protein 74 Homolog antibodyAnti-Capillary Morphogenesis Gene 1 Protein antibodyAnti-Cmg-1 antibodyAnti-Coiled-Coil Domain-Containing Protein 2 antibodyAnti-IFT74 antibodyAnti-CCDC2 antibodyAnti-CMG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance