Anti-IFT74 antibody (STJA0008376)

SKU:
STJA0008376
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Intraflagellar transport protein 74 homolog is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IFT74
Gene ID: 80173
Uniprot ID: IFT74_HUMAN
Specificity: This antibody detects endogenous levels of IFT74 at Human, Mouse
Immunogen: Synthesized peptide derived from human IFT74
Function Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis. Essential for flagellogenesis during spermatogenesis.
Protein Name Intraflagellar Transport Protein 74 Homolog
Capillary Morphogenesis Gene 1 Protein
Cmg-1
Coiled-Coil Domain-Containing Protein 2
Database Links Reactome: R-HSA-5620924
Cellular Localisation Cell Projection
Cilium
Cytoplasmic Vesicle
Flagellum
Secretory Vesicle
Acrosome
Localizes Along Primary Cilia At Interphase And Around The Basal Body/Centriole At Interphase And Mitosis
In Male Germ Cells
Strongly Expressed In The Vesicles Of Spermatocytes And Round Spermatids And Also In The Acrosome And Centrosome Regions Of Elongating Spermatids And In Developing Sperm Tails
Alternative Antibody Names Anti-Intraflagellar Transport Protein 74 Homolog antibody
Anti-Capillary Morphogenesis Gene 1 Protein antibody
Anti-Cmg-1 antibody
Anti-Coiled-Coil Domain-Containing Protein 2 antibody
Anti-IFT74 antibody
Anti-CCDC2 antibody
Anti-CMG1 antibody

Information sourced from Uniprot.org

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