| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IDUA |
| Gene ID: | 3425 |
| Uniprot ID: | IDUA_HUMAN |
| Immunogen Region: | 354-653 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 354-653 of human IDUA (NP_000194.2). |
| Immunogen Sequence: | SYHPHPFAQRTLTARFQVNN TRPPHVQLLRKPVLTAMGLL ALLDEEQLWAEVSQAGTVLD SNHTVGVLASAHRPQGPADA WRAAVLIYASDDTRAHPNRS VAVTLRLRGVPPGPGLVYVT RYLDNGLCSPDGEWRRLGRP VFPTAEQFRRMRAAEDPVAA APRPLPAGGRLTLRPALRLP SLLLVHVCARPEKPPGQVTR LRALPLTQGQLVLVWSDEHV GSKCLWTYEIQFSQDGKAY |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | N-glycosylation at Asn-372 contributes to substrate binding and is required for full enzymatic activity. |
| Protein Name | Alpha-L-Iduronidase |
| Database Links | Reactome: R-HSA-2024096Reactome: R-HSA-2024101Reactome: R-HSA-2206302 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Alpha-L-Iduronidase antibodyAnti-IDUA antibody |
Information sourced from Uniprot.org