| Short Description : | Rabbit polyclonal anti-Little elongation complex subunit 2 (474-524) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:1000-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ICE2 |
| Gene ID: | 79664 |
| Uniprot ID: | ICE2_HUMAN |
| Immunogen: | Synthesized peptide derived from human NARG2 AA range: 474-524 |
| Immunogen Region: | 474-524 |
| Specificity: | This antibody detects endogenous levels of human NARG2 |
| Function | Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. |
| Protein Name | Little Elongation Complex Subunit 2Interactor Of Little Elongator Complex Ell Subunit 2Nmda Receptor-Regulated Protein 2 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | NucleusColocalizes With Coil In Subnuclear Cajal And Histone Locus BodiesTranslocates In The Lec Complex To Cajal And Histone Locus Bodies At Snrna Genes In A Ice1-Dependent MannerAssociates To Transcriptionally Active Chromatin At Snrna Genes |
| Alternative Antibody Names | Anti-Little Elongation Complex Subunit 2 antibodyAnti-Interactor Of Little Elongator Complex Ell Subunit 2 antibodyAnti-Nmda Receptor-Regulated Protein 2 antibodyAnti-ICE2 antibodyAnti-BRCC1 antibodyAnti-NARG2 antibodyAnti-UNQ3101 antibodyAnti-PRO10100 antibody |
Information sourced from Uniprot.org
