Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Little elongation complex subunit 2 (474-524) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:1000-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ICE2 |
Gene ID: |
79664 |
Uniprot ID: |
ICE2_HUMAN |
Immunogen Region: |
474-524 |
Specificity: |
This antibody detects endogenous levels of human NARG2 |
Immunogen: |
Synthesized peptide derived from human NARG2 AA range: 474-524 |
Function | Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. |
Protein Name | Little Elongation Complex Subunit 2Interactor Of Little Elongator Complex Ell Subunit 2Nmda Receptor-Regulated Protein 2 |
Database Links | Reactome: R-HSA-6807505 |
Cellular Localisation | NucleusColocalizes With Coil In Subnuclear Cajal And Histone Locus BodiesTranslocates In The Lec Complex To Cajal And Histone Locus Bodies At Snrna Genes In A Ice1-Dependent MannerAssociates To Transcriptionally Active Chromatin At Snrna Genes |
Alternative Antibody Names | Anti-Little Elongation Complex Subunit 2 antibodyAnti-Interactor Of Little Elongator Complex Ell Subunit 2 antibodyAnti-Nmda Receptor-Regulated Protein 2 antibodyAnti-ICE2 antibodyAnti-BRCC1 antibodyAnti-NARG2 antibodyAnti-UNQ3101 antibodyAnti-PRO10100 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance