Anti-ICE2 antibody (474-524) (STJA0006645)

SKU:
STJA0006645

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Little elongation complex subunit 2 (474-524) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ICE2
Gene ID: 79664
Uniprot ID: ICE2_HUMAN
Immunogen Region: 474-524
Specificity: This antibody detects endogenous levels of human NARG2
Immunogen: Synthesized peptide derived from human NARG2 AA range: 474-524
Function Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
Protein Name Little Elongation Complex Subunit 2
Interactor Of Little Elongator Complex Ell Subunit 2
Nmda Receptor-Regulated Protein 2
Database Links Reactome: R-HSA-6807505
Cellular Localisation Nucleus
Colocalizes With Coil In Subnuclear Cajal And Histone Locus Bodies
Translocates In The Lec Complex To Cajal And Histone Locus Bodies At Snrna Genes In A Ice1-Dependent Manner
Associates To Transcriptionally Active Chromatin At Snrna Genes
Alternative Antibody Names Anti-Little Elongation Complex Subunit 2 antibody
Anti-Interactor Of Little Elongator Complex Ell Subunit 2 antibody
Anti-Nmda Receptor-Regulated Protein 2 antibody
Anti-ICE2 antibody
Anti-BRCC1 antibody
Anti-NARG2 antibody
Anti-UNQ3101 antibody
Anti-PRO10100 antibody

Information sourced from Uniprot.org

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