| Host: |
Mouse |
| Applications: |
WB/IHC-P/ELISA/FC/ICC |
| Reactivity: |
Human/Cow/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-CD54 is suitable for use in Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
MEM 111 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2a |
| Formulation: |
Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Immunogen: |
Raji human Burkitt's lymphoma cell line |
| Background | CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B-and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
