![Anti-ICAM-1 antibody [MEM 111] (STJ16100067)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/148785/346515/STJ16100067_1__54126.1681998545.jpg?c=1 "Anti-ICAM-1 antibody [MEM 111] (STJ16100067)")
![Anti-ICAM-1 antibody [MEM 111] (STJ16100067)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/148785/346515/STJ16100067_1__54126.1681998545.jpg?c=1 "Anti-ICAM-1 antibody [MEM 111] (STJ16100067)")
| Host: | Mouse |
| Applications: | WB/IHC-P/ELISA/FC/ICC |
| Reactivity: | Human/Cow/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CD54 is suitable for use in Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | MEM 111 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Immunogen: | Raji human Burkitt's lymphoma cell line |
| Background | CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B-and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. |
Information sourced from Uniprot.org