| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HSPB8 |
| Gene ID: | 26353 |
| Uniprot ID: | HSPB8_HUMAN |
| Immunogen Region: | 1-196 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-196 of human HSPB8/HSP22 (NP_055180.1). |
| Immunogen Sequence: | MADGQMPFSCHYPSRLRRDP FRDSPLSSRLLDDGFGMDPF PDDLTASWPDWALPRLSSAW PGTLRSGMVPRGPTATARFG VPAEGRTPPPFPGEPWKVCV NVHSFKPEELMVKTKDGYVE VSGKHEEKQQEGGIVSKNFT KKIQLPAEVDPVTVFASLSP EGLLIIEAPQVPPYSTFGES SFNNELPQDSQEVTCT |
| Tissue Specificity | Predominantly expressed in skeletal muscle and heart. |
| Function | Displays temperature-dependent chaperone activity. |
| Protein Name | Heat Shock Protein Beta-8 Hspb8 Alpha-Crystallin C Chain E2-Induced Gene 1 Protein Heat Shock Protein Family B Member 8 Protein Kinase H11 Small Stress Protein-Like Protein Hsp22 |
| Database Links | Reactome: R-HSA-3371571 |
| Cellular Localisation | Cytoplasm Nucleus Translocates To Nuclear Foci During Heat Shock |
| Alternative Antibody Names | Anti-Heat Shock Protein Beta-8 antibody Anti-Hspb8 antibody Anti-Alpha-Crystallin C Chain antibody Anti-E2-Induced Gene 1 Protein antibody Anti-Heat Shock Protein Family B Member 8 antibody Anti-Protein Kinase H11 antibody Anti-Small Stress Protein-Like Protein Hsp22 antibody Anti-HSPB8 antibody Anti-CRYAC antibody Anti-E2IG1 antibody Anti-HSP22 antibody Anti-PP1629 antibody |
Information sourced from Uniprot.org