| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S3MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HSPA12A |
| Gene ID: | 259217 |
| Uniprot ID: | HS12A_HUMAN |
| Immunogen Region: | 50-150 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human HSPA12A (O43301). |
| Immunogen Sequence: | SEQQSFLVVVAVDFGTTSSG YAYSFTKEPECIHVMRRWEG GDPGVSNQKTPTTILLTPER KFHSFGYAARDFYHDLDPNE AKQWLYLEKFKMKLHTTGDL T |
| Tissue Specificity | Widely expressed with highest levels in brain, kidney and muscle. |
| Function | Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization. |
| Protein Name | Heat Shock 70 Kda Protein 12aHeat Shock Protein Family A Member 12a |
| Database Links | Reactome: R-HSA-3371453 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Heat Shock 70 Kda Protein 12a antibodyAnti-Heat Shock Protein Family A Member 12a antibodyAnti-HSPA12A antibodyAnti-KIAA0417 antibody |
Information sourced from Uniprot.org