| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-HSH2D (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 37kDa band observed in lysates of cell line K562 (calculated MW of 39.0kDa according to NP_116244.1). Recommended concentration: 0.3-1µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HSH2D |
| Gene ID: | 84941 |
| Uniprot ID: | HSH2D_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_116244.1 |
| Immunogen Sequence: | HSHVGYTLSYKAQ |
| Post Translational Modifications | May be phosphorylated by FES and ACK1. |
| Function | May be a modulator of the apoptotic response through its ability to affect mitochondrial stability. Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. |
| Protein Name | Hematopoietic Sh2 Domain-Containing ProteinHematopoietic Sh2 ProteinAdaptor In Lymphocytes Of Unknown Function X |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Hematopoietic Sh2 Domain-Containing Protein antibodyAnti-Hematopoietic Sh2 Protein antibodyAnti-Adaptor In Lymphocytes Of Unknown Function X antibodyAnti-HSH2D antibodyAnti-ALX antibody |
Information sourced from Uniprot.org