Anti-HSD3B2 antibody (1-287) (STJ26181)

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STJ26181
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Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:1000
IF/ICC:1:10-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:HSD3B2
Gene ID:3284
Uniprot ID:3BHS2_HUMAN
Immunogen Region:1-287
Immunogen Sequence:MGWSCLVTGAGGLLGQRIVR LLVEEKELKEIRALDKAFRP ELREEFSKLQNRTKLTVLEG DILDEPFLKRACQDVSVVIH TACIIDVFGVTHRESIMNVN VKGTQLLLEACVQASVPVFI YTSSIEVAGPNSYKEIIQNG HEEEPLENTWPTPYPYSKKL AEKAVLAANGWNLKNGDTLY TCALRPTYIYGEGGPFLSAS INEALNNNGILSSVGKFSTV NPVYVGNVAWAHILALRAL
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human HSD3B2 (NP_000189.1).
Tissue Specificity Expressed in adrenal gland, testis and ovary.
Function 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Protein Name 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2
3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type Ii
3-Beta-Hsd Ii
3-Beta-Hsd Adrenal And Gonadal Type Includes - 3-Beta-Hydroxy-Delta(5-Steroid Dehydrogenase
3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase
Progesterone Reductase - Steroid Delta-Isomerase
Delta-5-3-Ketosteroid Isomerase
Database Links Reactome: R-HSA-193048
Reactome: R-HSA-193993
Reactome: R-HSA-194002
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Mitochondrion Membrane
Alternative Antibody Names Anti-3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2 antibody
Anti-3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type Ii antibody
Anti-3-Beta-Hsd Ii antibody
Anti-3-Beta-Hsd Adrenal And Gonadal Type Includes - 3-Beta-Hydroxy-Delta(5-Steroid Dehydrogenase antibody
Anti-3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase antibody
Anti-Progesterone Reductase - Steroid Delta-Isomerase antibody
Anti-Delta-5-3-Ketosteroid Isomerase antibody
Anti-HSD3B2 antibody
Anti-HSDB3B antibody

Information sourced from Uniprot.org