Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-HSD3B2 (1-287) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:100-1:500IF/ICC 1:10-1:100 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HSD3B2 |
Gene ID: |
3284 |
Uniprot ID: |
3BHS2_HUMAN |
Immunogen Region: |
1-287 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human HSD3B2 (NP_000189.1). |
Immunogen Sequence: |
MGWSCLVTGAGGLLGQRIVR LLVEEKELKEIRALDKAFRP ELREEFSKLQNRTKLTVLEG DILDEPFLKRACQDVSVVIH TACIIDVFGVTHRESIMNVN VKGTQLLLEACVQASVPVFI YTSSIEVAGPNSYKEIIQNG HEEEPLENTWPTPYPYSKKL AEKAVLAANGWNLKNGDTLY TCALRPTYIYGEGGPFLSAS INEALNNNGILSSVGKFSTV NPVYVGNVAWAHILALRAL |
Tissue Specificity | Expressed in adrenal gland, testis and ovary. |
Function | 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. |
Protein Name | 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 23 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type Ii3-Beta-Hsd Ii3-Beta-Hsd Adrenal And Gonadal Type Includes - 3-Beta-Hydroxy-Delta(5-Steroid Dehydrogenase3-Beta-Hydroxy-5-Ene Steroid DehydrogenaseProgesterone Reductase - Steroid Delta-IsomeraseDelta-5-3-Ketosteroid Isomerase |
Database Links | Reactome: R-HSA-193048Reactome: R-HSA-193993Reactome: R-HSA-194002 |
Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinMitochondrion Membrane |
Alternative Antibody Names | Anti-3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2 antibodyAnti-3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type Ii antibodyAnti-3-Beta-Hsd Ii antibodyAnti-3-Beta-Hsd Adrenal And Gonadal Type Includes - 3-Beta-Hydroxy-Delta(5-Steroid Dehydrogenase antibodyAnti-3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase antibodyAnti-Progesterone Reductase - Steroid Delta-Isomerase antibodyAnti-Delta-5-3-Ketosteroid Isomerase antibodyAnti-HSD3B2 antibodyAnti-HSDB3B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance