| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-HSD17B3 (141-155) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1-3µg/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
HSD17B3 |
| Gene ID: |
3293 |
| Uniprot ID: |
DHB3_HUMAN |
| Immunogen Region: |
141-155 |
| Accession Number: |
NP_000188.1 |
| Immunogen Sequence: |
SHFLNAPDEIQSLIH |
| Function | Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids. Favors the reduction of androstenedione to testosterone. Testosterone is the key androgen driving male development and function. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms. |
| Protein Name | 17-Beta-Hydroxysteroid Dehydrogenase Type 317-Beta-Hsd 3Estradiol 17-Beta-Dehydrogenase 2Short Chain Dehydrogenase/Reductase Family 12c Member 2Testicular 17-Beta-Hydroxysteroid DehydrogenaseTestosterone 17-Beta-Dehydrogenase 3 |
| Database Links | Reactome: R-HSA-193048Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-17-Beta-Hydroxysteroid Dehydrogenase Type 3 antibodyAnti-17-Beta-Hsd 3 antibodyAnti-Estradiol 17-Beta-Dehydrogenase 2 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 12c Member 2 antibodyAnti-Testicular 17-Beta-Hydroxysteroid Dehydrogenase antibodyAnti-Testosterone 17-Beta-Dehydrogenase 3 antibodyAnti-HSD17B3 antibodyAnti-EDH17B3 antibodyAnti-SDR12C2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
