Anti-HSD17B13 antibody (30-211) [S4159RM] (STJ11104159)

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STJ11104159
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Applications:WB/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :S4159RM
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:HSD17B13
Gene ID:345275
Uniprot ID:DHB13_HUMAN
Immunogen Region:30-211
Immunogen Sequence:RRKSVAGEIVLITGAGHGIG RQTTYEFAKRQSILVLWDIN KRGVEETAAECRKLGVTAHA YVVDCSNREEIYRSLNQVKK EVGDVTIVVNNAGTVYPADL LSTKDEEITKTFEVNILGHF WITKALLPSMMERNHGHIVT VASVCGHEGIPYLIPYCSSK FAAVGFHRGLTSELQALGKT GI
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 30-211 of human HSD17B13 (NP_835236.2).
Tissue Specificity Highly expressed in the liver. Also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis.
Function Plays a pivotal role in hepatic lipid metabolism. In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4. Isoform 2: Has retinol/retinal dehydrogenase activity in vitro. Isoform 1: Does not have retinol/retinal dehydrogenase activity in vitro.
Protein Name 17-Beta-Hydroxysteroid Dehydrogenase 13
17-Beta-Hsd 13
Hepatic Retinol/Retinal Dehydrogenase
Short Chain Dehydrogenase/Reductase Family 16c Member 3
Short-Chain Dehydrogenase/Reductase 9
Database Links Reactome: R-HSA-8964572
Cellular Localisation Isoform 2: Lipid Droplet
Endoplasmic Reticulum
Redistributed From The Endoplasmic Reticulum To Lipids Droplets In The Cell Upon Induction Of Lipids Droplet Formation
Isoform 1: Cytoplasm
Does Not Localize To Lipid Droplets
Alternative Antibody Names Anti-17-Beta-Hydroxysteroid Dehydrogenase 13 antibody
Anti-17-Beta-Hsd 13 antibody
Anti-Hepatic Retinol/Retinal Dehydrogenase antibody
Anti-Short Chain Dehydrogenase/Reductase Family 16c Member 3 antibody
Anti-Short-Chain Dehydrogenase/Reductase 9 antibody
Anti-HSD17B13 antibody
Anti-SCDR9 antibody
Anti-SDR16C3 antibody
Anti-HMFN0376 antibody
Anti-UNQ497 antibody
Anti-PRO1014 antibody

Information sourced from Uniprot.org