Anti-HRASLS/H-REV107 antibody (N-Term) (STJ71471)

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STJ71471-100
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Covered by St John's Laboratory Guarantee

Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-HRASLS/H-REV107 (N-Term) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:4000.
WB: Preliminary experiments in Human Heart, Skeletal Muscle and Thyroid Gland lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml).
IHC: Paraffin
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PLAAT1
Gene ID: 57110
Uniprot ID: PLAT1_HUMAN
Immunogen Region: N-Term
Accession Number: NP_065119.1
Immunogen Sequence: NDCFSLNYPGNPCP
Function Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE) which serves as precursor for N-acylethanolamines (NAEs).
Protein Name Phospholipase A And Acyltransferase 1
Hras-Like Suppressor 1
Hrsl1
Phospholipid-Metabolizing Enzyme A-C1
Database Links Reactome: R-HSA-1482839
Cellular Localisation Isoform 1: Membrane
Single-Pass Membrane Protein
Cytoplasm
Isoform 2: Nucleus
Alternative Antibody Names Anti-Phospholipase A And Acyltransferase 1 antibody
Anti-Hras-Like Suppressor 1 antibody
Anti-Hrsl1 antibody
Anti-Phospholipid-Metabolizing Enzyme A-C1 antibody
Anti-PLAAT1 antibody
Anti-HRASLS antibody

Information sourced from Uniprot.org

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