Anti-HRASLS/H-REV107 antibody (N-Term) (STJ71471)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-HRASLS/H-REV107 (N-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Preliminary experiments in Human Heart, Skeletal Muscle and Thyroid Gland lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml).IHC: Paraffin |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PLAAT1 |
| Gene ID | 57110 |
| Uniprot ID | PLAT1_HUMAN |
| Accession Number | NP_065119.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | NDCFSLNYPGNPCP |
Additional Info
| Function | Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE) which serves as precursor for N-acylethanolamines (NAEs). |
| Protein Name | Phospholipase A And Acyltransferase 1 Hras-Like Suppressor 1Hrsl1Phospholipid-Metabolizing Enzyme A-C1 |
| Database Links | Reactome: R-HSA-1482839 |
| Cellular Localisation | Isoform 1: MembraneSingle-Pass Membrane ProteinCytoplasmIsoform 2: Nucleus |
| Alternative Antibody Names | Anti-Phospholipase A And Acyltransferase 1 antibodyAnti-Hras-Like Suppressor 1 antibodyAnti-Hrsl1 antibodyAnti-Phospholipid-Metabolizing Enzyme A-C1 antibodyAnti-PLAAT1 antibodyAnti-HRASLS antibody |
Information sourced from Uniprot.org