| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HOXA9 |
| Gene ID: | 3205 |
| Uniprot ID: | HXA9_HUMAN |
| Immunogen Region: | 1-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human HOXA9 (NP_689952.1). |
| Immunogen Sequence: | MATTGALGNYYVDSFLLGAD AADELSVGRYAPGTLGQPPR QAATLAEHPDFSPCSFQSKA TVFGASWNPVHAAGANAVPA AVYHHHHHHPYVHPQAPVAA AAPDGRYMRSWLEPTPGALS FAGLPSSRPYGIKPEPLSAR RGDCPTLDTHTLSLTDYACG SPPVDREKQPSEGAFSENNA ENESGGDKPP |
| Post Translational Modifications | Methylated on Arg-140 by PRMT5.methylation is critical for E-selectin induction. |
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of SELE/E-selectin and VCAM1 on the endothelial cells surface at sites of inflammation. Positively regulates EIF4E-mediated mRNA nuclear export and also increases the translation efficiency of ODC mRNA in the cytoplasm by competing with factors which repress EIF4E activity such as PRH. |
| Protein Name | Homeobox Protein Hox-A9Homeobox Protein Hox-1g |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Homeobox Protein Hox-A9 antibodyAnti-Homeobox Protein Hox-1g antibodyAnti-HOXA9 antibodyAnti-HOX1G antibody |
Information sourced from Uniprot.org