Anti-HOXA9 antibody (1-190) (STJ24072)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HOXA9 (1-190) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HOXA9 |
| Gene ID | 3205 |
| Uniprot ID | HXA9_HUMAN |
| Immunogen Region | 1-190 |
| Immunogen Sequence | MATTGALGNYYVDSFLLGAD AADELSVGRYAPGTLGQPPR QAATLAEHPDFSPCSFQSKA TVFGASWNPVHAAGANAVPA AVYHHHHHHPYVHPQAPVAA AAPDGRYMRSWLEPTPGALS FAGLPSSRPYGIKPEPLSAR RGDCPTLDTHTLSLTDYACG SPPVDREKQPSEGAFSENNA ENESGGDKPP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human HOXA9 (NP_689952.1). |
Additional Info
| Post Translational Modifications | Methylated on Arg-140 by PRMT5.methylation is critical for E-selectin induction. |
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of SELE/E-selectin and VCAM1 on the endothelial cells surface at sites of inflammation. Positively regulates EIF4E-mediated mRNA nuclear export and also increases the translation efficiency of ODC mRNA in the cytoplasm by competing with factors which repress EIF4E activity such as PRH. |
| Protein Name | Homeobox Protein Hox-A9Homeobox Protein Hox-1g |
| Database Links | |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Homeobox Protein Hox-A9 antibodyAnti-Homeobox Protein Hox-1g antibodyAnti-HOXA9 antibodyAnti-HOX1G antibody |
Information sourced from Uniprot.org