| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HNRNPM |
| Gene ID: | 4670 |
| Uniprot ID: | HNRPM_HUMAN |
| Immunogen Region: | 491-730 |
| Immunogen Sequence: | GFGLERMAAPIDRVGQTIER MGSGVERMGPAIERMGLSME RMVPAGMGAGLERMGPVMDR MATGLERMGANNLERMGLER MGANSLERMGLERMGANSLE RMGPAMGPALGAGIERMGLA MGGGGGASFDRAIEMERGNF GGSFAGSFGGAGGHAPGVAR KACQIFVRNLPFDFTWKMLK DKFNECGHVLYADIKMENGK SKGCGVVKFESPEVAERACR MMNGMKLSGREIDVRIDRN |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 491-730 of human HNRNPM (NP_005959.2). |
| Post Translational Modifications | Sumoylated. |
| Function | Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein MHnrnp M |
| Database Links | Reactome: R-HSA-6803529Reactome: R-HSA-72163Reactome: R-HSA-72203 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein M antibodyAnti-Hnrnp M antibodyAnti-HNRNPM antibodyAnti-HNRPM antibodyAnti-NAGR1 antibody |
Information sourced from Uniprot.org
