| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HNRNPAB |
| Gene ID: | 3182 |
| Uniprot ID: | ROAA_HUMAN |
| Immunogen Region: | 1-285 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human HNRPAB (NP_004490.2). |
| Immunogen Sequence: | MSEAGEEQPMETTGATENGH EAVPEGESPAGAGTGAAAGA GGATAAPPSGNQNGAEGDQI NASKNEEDAGKMFVGGLSWD TSKKDLKDYFTKFGEVVDCT IKMDPNTGRSRGFGFILFKD AASVEKVLDQKEHRLDGRVI DPKKAMAMKKDPVKKIFVGG LNPEATEEKIREYFGEFGEI EAIELPMDPKLNKRRGFVFI TFKEEEPVKKVLEKKFHTVS GSKCEIKVAQPKEVYQQQQ |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Dimethylation at Arg-322 is probably asymmetric. |
| Function | Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site. |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein A/BHnrnp A/BApobec1-Binding Protein 1Abbp-1 |
| Cellular Localisation | NucleusCytoplasmLocalized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein A/B antibodyAnti-Hnrnp A/B antibodyAnti-Apobec1-Binding Protein 1 antibodyAnti-Abbp-1 antibodyAnti-HNRNPAB antibodyAnti-ABBP1 antibodyAnti-HNRPAB antibody |
Information sourced from Uniprot.org