| Host: | Rabbit |
| Applications: | WB/IP/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HNRNPA0 |
| Gene ID: | 10949 |
| Uniprot ID: | ROA0_HUMAN |
| Immunogen Region: | 1-180 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HNRNPA0 (NP_006796.1). |
| Immunogen Sequence: | MENSQLCKLFIGGLNVQTSE SGLRGHFEAFGTLTDCVVVV NPQTKRSRCFGFVTYSNVEE ADAAMAASPHAVDGNTVELK RAVSREDSARPGAHAKVKKL FVGGLKGDVAEGDLIEHFSQ FGTVEKAEIIADKQSGKKRG FGFVYFQNHDAADKAAVVKF HPIQGHRVEVKKAVPKEDIY |
| Post Translational Modifications | Phosphorylated at Ser-84 by MAPKAPK2 in response to LPS treatment, promoting stabilization of GADD45A mRNA. Arg-291 is dimethylated, probably to asymmetric dimethylarginine. |
| Function | mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs. |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein A0Hnrnp A0 |
| Cellular Localisation | NucleusComponent Of Ribonucleosomes |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein A0 antibodyAnti-Hnrnp A0 antibodyAnti-HNRNPA0 antibodyAnti-HNRPA0 antibody |
Information sourced from Uniprot.org