| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-HMG20A (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: This antibody has been successfully used in Rat Brain as described in the following paper: Artegiani et al, J Biol Chem. 2010 Aug 6;285 (32) :24740-50.; PMID: 20530487.IHC: In par |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HMG20A |
| Gene ID: | 10363 |
| Uniprot ID: | HM20A_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_060670.1 |
| Immunogen Sequence: | ATVREVVNRLDR |
| Function | Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4. |
| Protein Name | High Mobility Group Protein 20aHmg Box-Containing Protein 20aHmg Domain-Containing Protein 1Hmg Domain-Containing Protein Hmgx1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-High Mobility Group Protein 20a antibodyAnti-Hmg Box-Containing Protein 20a antibodyAnti-Hmg Domain-Containing Protein 1 antibodyAnti-Hmg Domain-Containing Protein Hmgx1 antibodyAnti-HMG20A antibodyAnti-HMGX1 antibodyAnti-HMGXB1 antibody |
Information sourced from Uniprot.org