Anti-HLA-DR1 antibody [MEM-267] (STJ16100939)

Anti-HLA-DR1 antibody [MEM-267] (STJ16100939)

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STJ16100939-01
£431.50
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: WB/FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-HLA-DR1 is suitable for use in Western Blot, Flow Cytometry and ELISA research applications.
Clonality : Monoclonal
Clone ID : MEM-267
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration: 1 mg/mL
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Purified, insoluble DR1 beta chain (DRB1*0101) expressed in E. coli inclusion bodies.
Background HLA-DR1 belongs to the HLA class II beta chain paralogues. The MHC Class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB) , both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The beta chain is approximately 26-28 kDa. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.

Information sourced from Uniprot.org

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