| Function | Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. |
| Protein Name | Hla Class Ii Histocompatibility Antigen - Dm Beta ChainMhc Class Ii Antigen DmbReally Interesting New Gene 7 Protein |
| Database Links | Reactome: R-HSA-2132295 |
| Cellular Localisation | Late Endosome MembraneSingle-Pass Type I Membrane ProteinLysosome MembraneLocalizes To Late Endocytic CompartmentAssociates With Lysosome Membranes |
| Alternative Antibody Names | Anti-Hla Class Ii Histocompatibility Antigen - Dm Beta Chain antibodyAnti-Mhc Class Ii Antigen Dmb antibodyAnti-Really Interesting New Gene 7 Protein antibodyAnti-HLA-DMB antibodyAnti-DMB antibodyAnti-RING7 antibody |
Information sourced from Uniprot.org
