Anti-Histone H2A antibody (Internal) (STJ96865)

SKU:
STJ96865
£48.00 - £252.00
Processing The item has been added

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Histone H2A type 1 (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: H2AC11.H2AC13.H2AC15.H2AC16.H2AC17
Gene ID: 8329/8330/8332/8336/8969
Uniprot ID: H2A1_HUMAN
Immunogen Region: Internal
Specificity: Histone H2A Polyclonal Antibody detects endogenous levels of Histone H2A protein.
Immunogen: Synthesized peptide derived from the Internal region of human Histone H2A. 20-50
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Name Histone H2a Type 1
H2a.1
Histone H2a/Ptl
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-3214847
Reactome: R-HSA-3214858
Reactome: R-HSA-5689603
Reactome: R-HSA-5689880
Reactome: R-HSA-5689901
Reactome: R-HSA-9609690
Reactome: R-HSA-9610379
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Histone H2a Type 1 antibody
Anti-H2a.1 antibody
Anti-Histone H2a/Ptl antibody
Anti-H2AC11 antibody
Anti-H2AFP antibody
Anti-HIST1H2AG.H2AC13 antibody
Anti-H2AFC antibody
Anti-HIST1H2AI.H2AC15 antibody
Anti-H2AFD antibody
Anti-HIST1H2AK.H2AC16 antibody
Anti-H2AFI antibody
Anti-HIST1H2AL.H2AC17 antibody
Anti-H2AFN antibody
Anti-HIST1H2AM antibody

Information sourced from Uniprot.org