| Post Translational Modifications | The active form of HGFAC presents in the serum is derived from the COOH-terminal region of the precursor by the cleavage of bonds between Arg-372 and Val-373 and Arg-407 and Ile-408. |
| Function | Serine protease that hydrolyzes the inactive zymogen hepatocyte growth factor (HGFsc) to an activated disulfide-linked heterodimer, then initiating hepatocyte growth factor receptor signaling pathway. |
| Protein Name | Hepatocyte Growth Factor Activator Serine ProteaseHgf ActivatorHgfaHgfa Serine ProteaseSerine Protease Hgfac Cleaved Into - Hepatocyte Growth Factor Activator Short Chain - Hepatocyte Growth Factor Activator Long Chain |
| Database Links | Reactome: R-HSA-6806942 |
| Cellular Localisation | SecretedExists As An Inactive Zymogen In PlasmaExists As An Active Heterodimeric Form In Serum |
| Alternative Antibody Names | Anti-Hepatocyte Growth Factor Activator Serine Protease antibodyAnti-Hgf Activator antibodyAnti-Hgfa antibodyAnti-Hgfa Serine Protease antibodyAnti-Serine Protease Hgfac Cleaved Into - Hepatocyte Growth Factor Activator Short Chain - Hepatocyte Growth Factor Activator Long Chain antibodyAnti-HGFAC antibody |
Information sourced from Uniprot.org
