| Short Description : | Rabbit polyclonal HFM1 (1-240) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HFM1 |
| Gene ID: | 164045 |
| Uniprot ID: | HFM1_HUMAN |
| Immunogen Region: | 1-240 |
| Immunogen Sequence: | MLKSNDCLFSLENLFFEKPD EVENHPDNEKSLDWFLPPAP LISEIPDTQELEEELESHKL LGQEKRPKMLTSNLKITNED TNYISLTQKFQFAFPSDKYE QDDLNLEGVGNNDLSHVAGK LTYASQKYKNHIGTEIAPEK SVPDDTKLVNFAEDKGESTS VFRKRLFKISDNIHGSAYSN DNELDSHIGSVKIVQTEMNK GKSRNYSNSKQKFQYSANVF TANNAFSASEIGEGMFKAP |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HFM1 (NP_001017975.4). |
| Tissue Specificity | Preferentially expressed in testis and ovary. |
| Function | Required for crossover formation and complete synapsis of homologous chromosomes during meiosis. |
| Protein Name | Probable Atp-Dependent Dna Helicase Hfm1Dna 3'-5' Helicase Hfm1Sec63 Domain-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Probable Atp-Dependent Dna Helicase Hfm1 antibodyAnti-Dna 3'-5' Helicase Hfm1 antibodyAnti-Sec63 Domain-Containing Protein 1 antibodyAnti-HFM1 antibodyAnti-SEC3D1 antibody |
Information sourced from Uniprot.org
![Immunofluorescence analysis of U-2 OS cells using [KO Validated] NSDHL Rabbit polyclonal antibody (STJ119221) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/98093/381689/STJ119221_1__50370.1713149871.jpg?c=1 "Immunofluorescence analysis of U-2 OS cells using [KO Validated] NSDHL Rabbit polyclonal antibody (STJ119221) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
